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AN2967: Implementation of a Walk-Up High-Pressure Capillary Ion Chromatograph for the Fast Separation of Pharmaceutical Relevant Inorganic Anions (diabetes tablet)

Instrument Type: IC

The counter ion impacts the API drug’s efficacy, solubility, and toxicity, and therefore counter ion determinations are important to pharmaceutical companies during all stages of product development and as part of product quality monitoring. In this example, the chloride counter ion is determined in a water extract of a pharmaceutical drug tablet designed to treat Type II diabetes patients. Here fast chloride determinations were demonstrated on an IonPac AS19 capillary column using a walk-up high pressure capillary IC system.