Bulk Substance Analysis Using DART Source Coupled to LTQ XL Ion Trap and Q Exactive Focus Mass Spectrometers

Instrument Type: LCMSMS

Forensic laboratories perform bulk substance identification to support investigations in cases involving possession, trafficking, and manufacturing of illicit drugs. A variety of analytical techniques can be used, but mass spectrometry provides methodologies that produce rapid and confident results. We evaluated two analytical workflows using a DART (Direct Analysis in Real Time) ion source coupled to a LTQ XL ion trap mass spectrometer and a Q Exactive Focus hybrid quadrupole- Orbitrap MS. Pharmaceutical pills were analyzed to demonstrate method performance. For forensic use only.