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Simultaneous analysis of the basic drug Trimipramine and its counterion using the Thermo Scientific Acclaim Mixed-Mode WAX-1 HPLC column

Instrument Type: HPLC

The Thermo Scientific Acclaim Mixed-Mode WAX-1 retains trimipramine, a hydrophobic base, by reversed-phase interaction, and maleate, the hydrophilic counterion, by anion-exchange interaction. In this way, it can eliminate a separate test for the two components.

Fast determination of tricyclic antidepressants from human plasma using Thermo Scientific SOLA CX SPE and a Thermo Scientific Hypersil GOLD HPLC column

Instrument Type: HPLC

The Thermo Scientific HPLC system is applied for the determination of tricyclic antidepressants. The samples are prepared using Thermo Scientific SOLA CX solid phase extraction (SPE) cartridges, and the separation performed on a Thermo Scientific Hypersil GOLD HPLC column. For Research Use Only. Not for use in diagnostic procedures.