LC-MS/MS Method for the Rapid Analysis of Five Artificial Sweeteners Using a Core Enhanced Technology Column

Instrument Type: LCMSMS

Acesulfame potassium, saccharin, aspartame, and sucralose are all commonly used artificial sweeteners that have been approved for use by the United States Food and Drug Administration (FDA). Sodium cyclamate has been banned in the United States, although it is approved for use in many other countries, including the UK. We demonstrate the use of the Thermo Scientific Accucore RP-MS HPLC column for the rapid analysis of five artificial sweeteners.

Separation and determination of acesulfame K and sucralose in beer using a polar embedded HPLC column with RI detection

Instrument Type: HPLC

The Thermo Scientific Dionex UltiMate 3000 LC system is applied for the separation and determination of acesulfame K and sucralose in beer. The separation was performed on a Thermo Scientific Acclaim Polar Advantage II (PA2) HPLC column. The results obtained for resolution between acesulfame K and sucralose was greater than 5 and tailing factor were less than 2.0 for both compounds.