AU158: Determination of Manganese in Brine

Instrument Type: IC

Sodium chloride brines are used in chlor-alkali cells and must have low concentrations of alkali and alkaline earth metals to prevent membrane poisoning. When brines are prepared from seawater, the manganese concentration is also a concern. This application update uses the same separation conditions as AN 120, but alters the online sample preparation with the MetPac column to effectively concentrate manganese from 10 times more sample than used in AN 120.

AN249: Determination of Methacholine Chloride and Potential Impurities Using a Reagent-Free Ion Chromatography System

Instrument Type: IC

This work presents IC-based methods for the detection and quantification of methacholine and possible impurities in solutions used to assess bronchial asthma of subjects evaluated in respiratory function labs and epidemiological field studies. Methacholine assay involves diluting the original solution (dissolved in 0.9% sodium chloride with or without 0.4% phenol) 1000-fold with deionized water, then analyzing the sample on a cation RFIC system. These methods demonstrate high precision and accuracy for both methacholine and possible impurities present in amounts approaching 1%.