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Displaying 1-2 of 2 results for Tag: Simvastatin

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Separation of related impurities from Combination drug of Ezetimibe and Simvastatin

Instrument Type: HPLC

The Thermo Scientific Dionex UltiMate 3000 LC system is applied for the separation of related impurities separation of combination drug of Ezetimibe and simvastatin. The separation was performed on a Thermo Scientific Hypersil Gold PFP column with UV detection at 238 nm. With a total run time of 120 minutes the method allows separation of all related impurities of Ezetimibe and Simvastatin.

Rapid screening method for statins using an advanced solid core UHPLC column and system combination

Instrument Type: UHPLC

Demonstration of the advantages of using the Thermo Scientific Accucore Vanquish C18+, 1.5 μm column and Thermo Scientific Vanquish UHPLC system for the fast analysis of statins. The advanced capabilities of the Vanquish UHPLC system allow the Accucore Vanquish columns to be operated at high flow rates that enable development of rapid analytical methods while maintaining high performance.