Identification and Quantitation of Plastic Additives in Medicine Containers by HR LCMS, GCMS and ICPMS

Instrument Type: LCMSMS

Purpose: Identification and Quantitation of Plastics Additives in Medicine Containers by HR LCMS, GCMS and ICPMS. Methods: HR-LCMS, GCMS and ICPMS and data processing software. Results: Comprehensive analysis of extractable for medicine container by multiple techniques, and data analysis software. Confident component detection, unknown structure identification, and quantification were achieved.

Determination of the Molecular Transformations and Pathways that Occur During the Winemaking Process

Instrument Type: LCMSMS

Direct wine analysis was used to determine the molecular weight of the components and their variable content across the 5 samples in this study was observed. This work demonstrates the utility of analyzing complex mixtures without prior sample preparation by making use of the separation of HPLC combined with the High Resolution Accurate Mass (HRAM) of the Q Exactive quadrupole Orbitrap mass analyzer. The combination of these techniques provides a robust and confident means of profiling complex mixtures as well as successful identification of detected components.

Metabolomic Analysis of Green and Black Tea Extracts Using an LTQ Orbitrap XL Hybrid Linear Ion Trap Mass Spectrometer

Instrument Type: LCMSMS

We demonstrate a complete analytical metabolomic workflow including (1) data acquisition using a high resolution accurate mass instrument that is equipped with a Higher Energy Collisional Dissociation (HCD) cell and coupled to a high pressure LC (Figure 1), (2) metabolite differential abundance analysis, and (3) structural elucidation of relevant metabolites using accurate mass and HCD fragmentation information to highlight the component differences between green and black tea.