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Reaction monitoring of fexofenadine API using a PFP HPLC column

Instrument Type: HPLC

The Thermo Scientific Dionex Ultimate 3000 HPLC system was applied for the reaction monitoring of fexofenadine and its impurities during the synthesis of fexofenadine API. The separation was performed on a Thermo Scientific Accucore PFP HPLC column resolution of 2.5 between fexofenadine and its meta isomer was achieved.