Highly Selective Detection and Identification of Nitrofuran Metabolites in Honey Using LC-MS/MS

Instrument Type: LCMSMS

Nitrofurans are broad-spectrum antibiotics used to treat bees and other animals with bacterial infections. Nitrofurans have been banned from use in food-producing animals in several countries. Several studies have shown that animals rapidly metabolize nitrofurans within a few hours so detection has focused on the metabolites rather than the native drug. We describe a method to accurately quantitate nitrofuran metabolites at levels as low as 0.3 ppb in a matrix consisting of honey using the TSQ Quantum Discovery.

High-Throughput Food Safety Control Employing Real Time Ionization (DART) Coupled to Orbitrap High-Resolution Mass Spectrometry

Instrument Type: Unspecified

This application note shows the possibilities using the DART ion source coupled with the ultra high-resolution Thermo Scientific Exactive mass spectrometer for rapid detection and quantitation of a wide range of food contaminants like mycotoxins and food adulterants (melamine).