Quantitation of Opiates to Low ng/mL Levels in Urine for Forensic Use Using an Affordable, High-Resolution, Accurate-Mass Mass Spectrometer

Instrument Type: LCMSMS

Forensic toxicologists need an economical instrument capable of both screening a large number of compounds and quantifying smaller panels to industry-established limits. Here we present a method for quantitation of six opiates - morphine, codeine, hydromorphone, hydrocodone, oxymorphone, and oxycodone - in human urine down to low ng/mL levels. This work was performed on a Q Exactive Focus hybrid quadrupole Orbitrap mass spectrometer. For forensic use only.

Extraction and determination of oxymorphone and its isomer from human plasma using Thermo Scientific HyperSep SLE and a Thermo Scientific Hypersil GOLD HPLC column

Instrument Type: LCMS

The Thermo Scientific HPLC system is applied for the determination of oxymorphone and its isomer from human plasma. The samples are prepared using Thermo Scientific HyperSep solid supported liquid-liquid extraction (SLE), and the separation performed using a Thermo Scientific Hypersil GOLD HPLC column. For Research Use Only. Not for use in diagnostic procedures.