AN1000: Direct Determination of Small Organic Acids in Sea Water by IC-MS

Instrument Type: ICMS

This application demonstrates a 2D-IC-MS system that allows low levels of small organic acids (C1–5) to be analyzed in a high-ionic-strength matrix. The first dimension of the system separates the low-level analytes from the matrix while the second dimension resolves each of the target analytes. The mass spectrometer confirms identity and achieves low detection limits for a sensitive and selective assay. No special sample preparation was required and the results show good precision and reproducibility.

Rapid organic acid analysis using the Thermo Scientific Acclaim Surfactant Plus HPLC column

Instrument Type: HPLC

The Thermo Scientific Dionex UltiMate 3000 RSLC system is applied for the fast analysis of vitamin C and its decomposition products. The separation is performed isocratically on a Thermo Scientific Acclaim Surfactant Plus, with UV detection at 220 nm.

Enhanced separation of keto acids using the Thermo Scientific Acclaim Mixed-Mode WAX-1 HPLC column

Instrument Type: HPLC

The Thermo Scientific HPLC system is applied for the analysis of small organic acids. The separation is performed isocratically on a Thermo Scientific Acclaim Mixed-Mode WAX-1, with UV detection at 210 nm.