Determination of High Sugar Concentrations in a Malbec Wine Sample Using a Compact Ion Chromatography System

Instrument Type: IC

This record demonstrates the determinations of glucose in a 100-fold diluted Malbec wine sample by HPAE-PAD. Typically samples with g/L concentrations require > 10,000-fold dilutions to remain in the linear range of the very sensitive HPAE-PAD technique. However, this method, demonstrated on the Integrion RFIC system, uses a 0.4 µL internal injection loop with the High Concentration Carbohydrate Analysis Kit to extend the linearity from low mg/L to g/L concentrations. A wood hydrolysate application using this technique is attached for reference.

AB136 (a): Determination of Inorganic Counterions in Pharmaceutical Drugs Using Capillary IC

Instrument Type: IC

Approximately 50% of all drugs on the market are developed in salt forms. IC with suppressed conductivity detection plays an important role in the salt selection process to establish correct molecular mass of the entity in early stages of drug development. This study describes the determination of inorganic anions (a) and cations (b) in two different drugs using the capillary Thermo Scientific Dionex ICS-5000 system.

AB136 (b): Determination of Inorganic Counterions in Pharmaceutical Drugs Using Capillary IC

Instrument Type: IC

Approximately 50% of all drugs on the market are developed in salt forms. IC with suppressed conductivity detection plays an important role in the salt selection process to establish correct molecular mass of the entity in early stages of drug development. This study describes the determination of inorganic anions (a) and cations (b) in two different drugs using the capillary Thermo Scientific Dionex ICS-5000 system.