Quantitation of Opiates to Low ng/mL Levels in Urine for Forensic Use Using an Affordable, High-Resolution, Accurate-Mass Mass Spectrometer

Instrument Type: LCMSMS

Forensic toxicologists need an economical instrument capable of both screening a large number of compounds and quantifying smaller panels to industry-established limits. Here we present a method for quantitation of six opiates - morphine, codeine, hydromorphone, hydrocodone, oxymorphone, and oxycodone - in human urine down to low ng/mL levels. This work was performed on a Q Exactive Focus hybrid quadrupole Orbitrap mass spectrometer. For forensic use only.