Quantitative Forensic Analysis of Opiates, Opioids, and Their Metabolites in Human Urine Without Hydrolysis

Instrument Type: LCMSMS

Analysis of opiate and opioid metabolites in urine is most often done with a hydrolysis step that make total sample preparation time up to 24 hours. The method described here eliminates the hydrolysis step by analyzing the conjugated metabolites intact using a Thermo Scientific Prelude SPLC system for sample preparation and a Thermo Scientific TSQ Endura triple quadrupole mass spectrometer for analysis. For forensic use only.