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AN1121: Ion Chromatography Assay for Lithium in Lithium Citrate

Instrument Type: IC

This application note describes an ion chromatography (IC) based method that uses a Thermo Scientific™ Dionex™ IonPac™ CS12A-5µm cation-exchange column, an electrolytically generated MSA eluent, and suppressed conductivity detection to determine lithium in lithium citrate. The method proposed in this application note was validated following the guidelines outlined in USP General Chapter <1225>, Validation of Compendial Procedures.