Analysis of Immunosupressant Drugs in Whole Blood Using a High-Efficiency Method on an Affordable High-Resolution Mass Spectrometer

Instrument Type: LCMSMS

Clinical research labs commonly use selective and cost-efficient LC-MS techniques for the analysis of immunosupressants drugs. Usually, the quantitative method is developed on a triple quadrupole mass spectrometer. Here, we evaluated a high-efficiency method implemented on a Q Exactive Focus hybrid quadrupole Orbitrap mass spectrometer for improved selectivity when compared to the conventional solution.

Quantitation of Immunosuppressant Drugs in Whole Blood Using the Prelude-SPLC System and TSQ Endura Mass Spectrometer for Research

Instrument Type: LCMSMS

We developed a a rapid, sensitive, selective, and robust LC-MS/MS method to determine the concentrations of cyclosporine A, tacrolimus, sirolimus, and everolimus in whole blood.