AN173: Direct Determination of Cyanide in Drinking Water by Ion Chromatography with Pulsed Amperometric Detection (PAD)

Instrument Type: IC

Cyanide, a well known acute toxin, occurs both naturally and as an industrial contaminant. In the U.S., cyanide contamination in drinking water is typically from an industrial source or leached from waste sites. In EPA Method 335, samples are individually acid- or UV-digested to convert all cyanide compounds to hydrogen cyanide gas which is distilled into sodium hydroxide (pH 13). These high pH matrixes can cause interferences in spectrophotometric methods. Here free cyanide is separated by IC and detected electrochemically using Ag working electrode and waveform for cyanide determinations.

AU140: The Determination of Iodide in Urine

Instrument Type: IC

In this Application Update, ion chromatography coupled with pulsed amperometric detection is used to determine iodide in urine. This method is specific, sensitive, and rapid. Sample preparation involves removal of urine components with molecular weights greater than 10,000 daltons, sample dilution, and treatment with a polymeric, reversed-phase cartridge (OnGuard™-RP).