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Separation of related impurities from Combination drug of Ezetimibe and Simvastatin

Instrument Type: HPLC

The Thermo Scientific Dionex UltiMate 3000 LC system is applied for the separation of related impurities separation of combination drug of Ezetimibe and simvastatin. The separation was performed on a Thermo Scientific Hypersil Gold PFP column with UV detection at 238 nm. With a total run time of 120 minutes the method allows separation of all related impurities of Ezetimibe and Simvastatin.