Bulk Substance Analysis Using DART Source Coupled to LTQ XL Ion Trap and Q Exactive Focus Mass Spectrometers

Instrument Type: LCMSMS

Forensic laboratories perform bulk substance identification to support investigations in cases involving possession, trafficking, and manufacturing of illicit drugs. A variety of analytical techniques can be used, but mass spectrometry provides methodologies that produce rapid and confident results. We evaluated two analytical workflows using a DART (Direct Analysis in Real Time) ion source coupled to a LTQ XL ion trap mass spectrometer and a Q Exactive Focus hybrid quadrupole- Orbitrap MS. Pharmaceutical pills were analyzed to demonstrate method performance. For forensic use only.

Rapid, Automated, and Accurate Determination of Volatiles in Human Blood by Headspace Gas Chromatography

Instrument Type: GC

The purpose of this application is to describe the determination of blood alcohol levels by using the Trace 1310 GC in dual-column configuration, coupled with the new Triplus 300 Headspace Autosampler. Blood alchol content analysis is one of the most common test in forensic science and it is generally performed via headspace gas chromatography with flame ionization detection (FID). The use of Chromeleon CDS software is employed to easily perform the analysis in the dual-column / dual-FID configuration in a fully automated manner.