AN268: Determination of Chelating Agents in Drinking Water and Wastewater Samples

Instrument Type: IC

Aminopolycarboxylate chelating agents form stable water-soluble complexes with alkali and transition metal ions, thus increasing metal solubility and preventing metal-catalyzed reactions. In wastewater treatment plants, chelating agents can interfere with metal removal processes and contaminate the environment upon discharge. Here EDTA, NTA, DTPA, and EGTA chelating agents are determined at μg/L concentrations in municipal wastewater samples. The chelating agents are separated on a Dionex IonPac AS7 column using methanesulfonic acid and detected by PAD with a Pt working electrode.

AN289: Evaluation of the USP Risedronate Sodium Assay

Instrument Type: IC

Risedronate is a pyridinyl bisphosphonate that is used as a drug for the prevention and treatment of osteoporosis. Risedronate poses analytical challenges for reversed-phase (RP) high-performance liquid chromatography (HPLC) due to the presence of two polar phosphonate groups. This study evaluates and validates a USP monograph method for risedronate analysis using ion chromatography.