Fast isocratic method for the separation of basic drugs

Instrument Type: HPLC

The Thermo Scientific HPLC system is applied for the analysis of basic drugs. The separation is performed on a Thermo Scientific Acclaim 120 C18 column, with UV detection at 220 nm. This application is used as a routine lot qualification test for the Acclaim 120 C18 column stationary phase. Low silanol activity preserves the good peak shape for amitriptyline as the sample concentration decreases (amitriptyline mass for trace A is 1200 ng, for trace B is 400 ng, and for trace C 94 ng).

Fast analysis of five antidepressants using a Thermo Scientific Acclaim PolarAdvantage (PA) HPLC column

Instrument Type: HPLC

The Thermo Scientific HPLC system is applied for the determination of five antidepressants. The separation is performed on a Thermo Scientific Acclaim PolarAdvantage (PA) HPLC column, with UV detection at 220 nm.

Improved analysis of doxepin in human plasma using Thermo Scientific SOLA HRP SPE and a Thermo Scientific Accucore C18 HPLC column

Instrument Type: HPLC

The Thermo Scientific HPLC system is applied for the determination of doxepin in human plasma. The samples are prepared using Thermo Scientific SOLA HRP solid phase extraction (SPE) cartridges, and the separation performed on a Thermo Scientific Accucore C18 HPLC column. For Research Use Only. Not for use in diagnostic procedures.

Fast determination of tricyclic antidepressants from human plasma using Thermo Scientific SOLA CX SPE and a Thermo Scientific Hypersil GOLD HPLC column

Instrument Type: HPLC

The Thermo Scientific HPLC system is applied for the determination of tricyclic antidepressants. The samples are prepared using Thermo Scientific SOLA CX solid phase extraction (SPE) cartridges, and the separation performed on a Thermo Scientific Hypersil GOLD HPLC column. For Research Use Only. Not for use in diagnostic procedures.