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Related substances analysis of cefepime dihydrochloride hydrate using a C18 HPLC column as per JP XVI and KP X monograph method
Instrument Type: HPLCThe Thermo Scientific Dionex UltiMate 3000 LC system is applied for the related substances analysis of cefepime dihydrochloride hydrate. The analysis was performed on a Thermo Scientific Syncronis aQ HPLC column using the method described in the JP XVI and KP X. The results obtained for theoretical plates and %RSD for cefepime met the criteria stated in the JP/KP monograph. The results obtained for theoretical plates of cefepime was 54,132 (JP/KP criteria of not less than 6,000) and %RSD for cefepime was 0.1% (JP/KP criteria of not more than 2).