USP 38 monograph: impurity determination of carbamazepine using a cyano HPLC column

Instrument Type: HPLC

The Thermo Scientific Dionex UltiMate 3000 LC system is applied for the analysis of carbamazepine and its impurities. The separation was performed on a Thermo Scientific Hypersil Gold CN HPLC column using the method described in the USP 38 monograph. The results obtained for resolution exceeded the criteria stated in the USP. Resolution between carbamazepine related compound A and carbamazepine was 4.00 (USP criteria of not less than 1.70).

Reproducible separation of acidic and neutral drugs using a solid core C18 HPLC column

Instrument Type: HPLC

The separation of acidic and neutral drugs was successfully achieved on the Thermo Scientific Accucore C18 column, providing an excellent choice for the analysis of these drugs giving excellent retention time reproducibility and resolution.

Improved analysis of carbamazepines using a Thermo Scientific Hypersil GOLD C8 HPLC column

Instrument Type: HPLC

The Thermo Scientific HPLC system is applied for the analysis of carbamazepines. The separation is performed on a Thermo Scientific Hypersil GOLD C8 HPLC column, with UV detection at 230 nm.

Improved analysis of anticonvulsants using a Thermo Scientific Hypersil GOLD HPLC column

Instrument Type: HPLC

The Thermo Scientific HPLC system is applied for the analysis of anticonvulsants. The separation is performed on a Thermo Scientific Hypersil GOLD HPLC column, with UV detection at 205 nm.