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AN1078: Determination of Benzenesulfonic Acid Counterion in Amlodipine Besylate by Ion Chromatography

Instrument Type: IC

This study demonstrates the determination of benzenesulfonate in amlodipine besylate using an electrolytically generated potassium hydroxide eluent with a hydroxide-selective Dionex IonPac AS18 anion exchange column and suppressed conductivity detection. This method provides a simple and reliable approach to determine the counter ion in the drug substance.