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HPLC (Biocompatible) UHPLC LCMS

BioPharma Clinical Research

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50 mM Sodium phosphate pH 6.8 + 300 mM NaCl Buffer Formulation Human plasma N/A NA

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4-Aminobenzoic acid (PABA) (0.137 kDa) Aflibercept Aggregate Aggregate 1 Aggregate 2 Aggregate 3 Aggregates Aggregrate Bevacizumab Bevacizumab-Aggregate Cetuximab Dimer Fragment 1 Fragment 2 Gamma-globulin (150 kDa) Gamma-globulin aggregate Lipids, DNA, large proteins Monomer Ovalbumin (44.3 kDa) Pertuzumab Ribonuclease A (13.7 kDa) Rituximab Teriperatide Monomer Thyroglobulin (670 kDa) Thyroglobulin aggregate Undigested protein aggregates and structural proteins Ustakinumab Monomer

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Class

Aggegate Aggregate biotherapeautic biotherapeautic degradation product Fragment IgG1 Immunoglobulin Impurity main peak Monoclonal antibody monomer Plasma Protein Protein Protein aggregate Substituted benzoic acid

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Manufacturer

Thermo Fisher Scientific Thermo Fisher Scientific™ Thermofisher Scientific

Model

Acclaim C18 MAbPac SEC -1 MabPac SEC-1

Stationary Phase

300 Å proprietary diol C18 Selectivity Diol High-purity, spherical, porous (300 Å) silica Hydrophilic 300 A size-exclusion resin Prorietary diol Silica Silica, Spherical Fully Porous Type A Spherical, Fully Porous, Ultrapure Silica

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Displaying 1-5 of 14 results for: aggregate

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aggregate analysis fusion protein

Aggregate analysis of Fusion protein (Histalob) using a MAbPac™ SEC-1 column.

Instrument Type: HPLC (Biocompatible)

The Thermo Scientific Dionex UltiMate 3000 LC system is applied for the Aggregate analysis of Fusion protein. The analysis was performed on a Thermo Scientific MAbPac™ SEC-1 HPLC column using the UV detector.

aggregate analysis fusion protein

Aggregate analysis of Fusion protein (Bhargalob) using a MAbPac™ SEC-1 column.

Instrument Type: HPLC (Biocompatible)

The Thermo Scientific Dionex UltiMate 3000 LC system is applied for the Aggregate analysis of Fusion protein. The analysis was performed on a Thermo Scientific MAbPac™ SEC-1 HPLC column using the UV detector.

aggregate analysis

Ustakinumab aggregate amalysis using Mabpac SEC-1

Instrument Type: HPLC (Biocompatible)

The Thermo Scientific™ Ultimate3000™ Biointert UHPLC system was applied for the aggregate analysis of Ustekinumab using Mabpac SEC-1 column.

aggregate analysis teriparatide

Chromatographic method for size base impurity analysis of Teriparatide formulation sample using SEC Column

Instrument Type: HPLC (Biocompatible)

The Thermo Scientific Dionex Ultimate 3000 Bio LC System is applied for the impurity analysis of Teriparatide formulation sample. Analysis is performed on Mabpac SEC -1

filgrastim sec method

Chromatographic method for size base impurity analysis of Filgrastim

Instrument Type: HPLC (Biocompatible)

The Thermo Scientific Dionex ultimate 3000 Bio LC system is Applied for the Aggregate impurities analysis of Filgrastim. The analysis was performed on Mabpac SEC-1 using the IP monograph method. IP has revised the resolution criteira from 2.0 to 3.0. The critical resolution of Aggregate and monomer was more than 3.0 .

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