The determination of trace cationic contamination in processing acids (phosphoric, sulfuric, hydrofluoric) is important to the electronics industries to minimize corrosion. Here trace cationic contamination is determined in a 24% sulfuric acid sample. The acid sample is automatically neutralized through an electrolytic device, and then retained and concentrated onto a concentrator column. After eluting from the concentrator column, the µg/L cations are determined on an IonPac CS16 column using electrolytically generated MSA eluent and suppressed conductivity detection.
The determination of trace cationic contamination in processing acids (phosphoric, sulfuric, hydrofluoric) is important to the electronics industries to minimize corrosion. Here trace cationic contamination is determined in a 25% phosphoric acid sample. The acid sample is automatically neutralized through an electrolytic device, and then retained and concentrated onto a concentrator column. After eluting from the concentrator column, the µg/L cations are determined on an IonPac CS16 column using electrolytically generated MSA eluent and suppressed conductivity detection.
The determination of trace cationic contamination in processing acids (phosphoric, sulfuric, hydrofluoric) is important to the electronics industries to minimize corrosion. Here trace cationic contamination is determined in a 10% hydrofluoric acid sample. The acid sample is automatically neutralized through an electrolytic device, and then retained and concentrated onto a concentrator column. After eluting from the concentrator column, the µg/L cations are determined on an IonPac CS16 column using electrolytically generated MSA eluent and suppressed conductivity detection.
Metformin (N,N-dimethylimidodicarbonimidic diamide) is a widely prescribed orally administered antidiabetic drug for the treatment of type 2 diabetes. This application presents a IC method used for quantitation of dimethylamine in metformin hydrochloride. This method uses a Thermo Scientific Dionex IonPac CS19 cation-exchange analytical column with methanesulfonic acid eluent produced by an eluent generator. The method separates dimethylamine from other cations typically present in drug products.