Veterinary drugs are pharmacologically active compounds that can result in non-desirable drug residues in the food chain. Animals with high amounts of these drugs can cause harm in humans or can render the use of antibiotics useless due to the counter effects of the drugs. The quantification of over 200 multi-class veterinary drugs from different meat products usually involves time consuming extraction methods with either SPE or LLE. We describe a robust method, utilizing a single LC-MS/MS run to quantitate over 200 veterinary drugs in a variety of matrices.
We developed an effective LC-MS/MS method to detect eight gluococorticoid residues in the liver and muscles of pig, cattle, and lamb, as well as in chicken, eggs and milk.
This application analyzes steroids in equine urine samples using a Thermo Scientific TSQ Quantiva triple quadrupole MS detector with a Thermo Scientific Vanquish UHPLC system.