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Displaying 1-5 of 2511 results

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Best practices for liposome analysis with the charged aerosol detector

Instrument Type: HPLC-CAD

This technical note is intended to demonstrate the use of the charged aerosol detector for liposome analysis with ASTM method E3297-21

AN73883 Determination of per- and polyfluorinated alkyl substances (PFAS) in drinking water Using automated solid phase extraction and LC-MS/MS for U.S. EPA Method 533

Instrument Type: LCMSMS

Drinking water perfluorinated and polyfluorinated alkyl substances (PFAS) studies have typically targeted PFOS and PFBA and other PFAS. Here we discuss the development of an analytical method using an automated SPE system and LC-MS/MS for determination of twenty-five PFAS compounds following the guidelines provided by U.S. EPA Method 533. We have demonstrated that the automated SPE system provides reliable determination of PFAS in large-volume aqueous samples and saves time, solvent, and labor, while ensuring high reproducibility and productivity for analytical testing laboratories.

AN73883 Determination of PFAS in drinking water Using automated solid phase extraction and LC-MS/MS for U.S. EPA Method 533

Instrument Type: Automated Sample Prep

Drinking water perfluorinated and polyfluorinated alkyl substances (PFAS) studies have typically targeted PFOS and PFBA and other PFAS. Here we discuss the development of an analytical method using an automated SPE system and LC-MS/MS for determination of twenty-five PFAS compounds following the guidelines provided by U.S. EPA Method 533. We have demonstrated that the automated SPE system provides reliable determination of PFAS in large-volume aqueous samples and saves time, solvent, and labor, while ensuring high reproducibility and productivity for analytical testing laboratories.

AN002771 LC-MS/MS analysis of per- and polyfluoroalkyl substances (PFAS) in soil samples in accordance with EPA Method 1633: semi-automated solid phase extraction cleanup

Instrument Type: LCMS

PFAS workflows are continuously being developed to meet evolving testing requirements for per- and polyfluoroalkyl substances (PFAS) worldwide. This work describes that workflow by leveraging the Dionex AutoTrace 280 PFAS SPE instrument to automate the soil sample solid-phase extraction (SPE) cleanup stage that is described in EPA Method 1633.

AN002338: Quantitation of per- and polyfluoroalkyl substances (PFAS) in aqueous samples by LC-MS/MS following EPA Draft Method 1633

Instrument Type: LCMS

PFAS are per- and polyfluoroalkyl substances. The chemical nature of the C-F bonds makes these compounds extremely stable. Hence, PFAS have been given the term “forever compounds”. This application note will present data for measuring 40 PFAS in fortified water samples following the third draft of EPA Method 1633. An MDL study was conducted in reagent water to demonstrate that equivalent or better performance can be attained using the Thermo Scientific™ Vanquish™ Flex Binary UHPLC system and Thermo Scientific™ TSQ™ Quantis Plus mass spectrometer.