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Related substances analysis of cefotaxime sodium using a polar end-capped C18 HPLC column as per EP 8.0 monograph method
Description
The Thermo Scientific Dionex UltiMate 3000 LC system is applied for the related substances analysis of Cefotaxime Sodium. The analysis was performed on a Thermo Scientific Syncronis aQ HPLC column using the method described in the EP 8.0. The results obtained for resolution and symmetry factor met the criteria stated in the EP. The results obtained for resolution between the peaks due to Impurity E and Cefotaxime was 6.7 (EP criteria of minimum 3.5) and asymmetry factor for cefotaxime was 1.1 (EP criteria of maximum 2).| Market: | Pharma |
| Keywords: | Cefotaxime, HPLC, Syncronis aQ, UV detection, EP 8.0 monograph |
| Matrix: | N/A |
| Author: | Krishnarao Dara |
| Affiliation: | Thermo Fisher Scientific, CoE Lab, Ahmedabad, India |
For Research Use Only. Not for use in diagnostic procedures.
