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Organic impurities analysis of Guaifenesin using a C18 type HPLC column as per USP 40 monograph and its fast analysis
Description
The Thermo Scientific Dionex UltiMate 3000 LC system is applied for the organic impurities analysis of Guaifenesin. The analysis was performed on a Thermo Scientific Hypersil GOLD (4.6 x 250 x 5 µ) as per the specified dimension and its fast analysis using Hypersil GOLD (2.1 x 100 x 1.9 µ) and Accucore RP-MS (3 x 150 x 2.6 µ) columns as per the method described in the USP 40 (refer attachment). The results obtained for resolution on all three columns met the criteria stated in the USP (USP criteria of minimum 3.0).| Market: | Pharma |
| Keywords: | Accucore RP-MS, HPLC, UV detection, Guaifenesin, Expectorant |
| Matrix: | N/A |
| Author: | Krishnarao Dara |
| Affiliation: | Thermo Fisher Scientific, CCS CoE Lab, Ahmedabad, India |
For Research Use Only. Not for use in diagnostic procedures.
