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Non-Targeted Screening of Lipophilic Marine Biotoxins by Liquid Chromatography-High-Resolution Mass Spectrometry
Description
Marine biotoxins are produced by naturally occurring microalgae, whose populations can increase significantly under certain environmental conditions to form a harmful algal bloom (HAB). Marine biotoxins pose a significant food safety risk when bioaccumulated in shellfish that are ingested by humans. We describe the use of the Thermo Scientific Exactive benchtop LC/MS system powered by Orbitrap technology for screening lipophilic marine biotoxins commonly found in shellfish. The method was optimized using a standard mixture of marine biotoxins, and then applied to a mussel tissue extract.| Market: | Environmental |
| Keywords: | Hypersil GOLD, Orbitrap Technology, Exactive, Liquid chromatography, Marine Biotoxin, Non-Targeted Screening |
| Matrix: | Mussel |
| Author: | Pearl Blay, Joseph P.M. Hui, Jeremy E. Melanson, James S. Chang |
| Affiliation: | National Research Council of Canada, Institute for Marine Biosciences, Halifax, Nova Scotia, Canada; Thermo Fisher Scientific |
For Research Use Only. Not for use in diagnostic procedures.
