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Increasing Speed of UHPLC-MS Analysis Using Single-stage Orbitrap Mass Spectrometer

Description
Productivity of an LC-MS system is measured in samples per day. Modern ultrahigh pressure LC-MS (UHPLC-MS) methods increasingly deal with very short gradients, leading to chromatographic signals with peak widths below 5 seconds at the base. It is still a challenge for high-resolution, accurate mass (HR/AM) systems to provide a sufficient number of scans (=10) across the chromatographic peak in full scan mode without compromising sensitivity and selectivity. We describe a system that addresses these challenges.Market: | Environmental |
Keywords: | HRAM, Pesticide Screening, Exactive Plus, Feed analysis |
Matrix: | Animal feed |
Author: | Olaf Scheibner and Maciej Bromirski |
Affiliation: | Thermo Fisher Scientific |
For Research Use Only. Not for use in diagnostic procedures.