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EP 8.0 monograph: impurity determination of cefradine using reversed-phase HPLC-UV
Description
The Thermo Scientific Dionex UltiMate 3000 LC system is applied for the analysis of Cefradine and its impurities. The separation was performed on a Thermo Scientific Hypersil Gold column using the method described in the EP 8.0 monograph. Resolution between cefalexin and cefradine was 7.3 (EP criteria of minimum 4.0). Retention time of cefradine was 15.1 minutes (EP criteria of about 15 minutes). The criteria for relative retention time were also exceeded.| Market: | Pharma |
| Keywords: | HPLC, Hypersil GOLD, UV detection, EP 8.0 monograph, Cefradine, Cefalexin |
| Matrix: | N/A |
| Author: | Manish Singh |
| Affiliation: | Thermo Fisher Scientific |
For Research Use Only. Not for use in diagnostic procedures.
