Fast Nevirapine Impurity Profiling Using UHPLC-DAD

Instrument Type: UHPLC

This application describes an optimized method for the impurity profiling of nevirapine using a ballistic gradient method.The separation is completed in 2.8 min, compared to 80 min of the isocratic USP method. The Vanquish UHPLC system easily enables the simultaneous detection of the API and related impurities while achieving compliance with the ICH guidelines on impurity monitoring.