AN123: Determination of Inorganic Anions and Organic Acids in Fermentation Broths

Instrument Type: IC

Fermentation broths are complex mixtures of nutrients, waste products, cells and cell debris, and desired products. Fermentation monitoring is important for many industries because carbon sources and metabolic by-products can impact the yield of the desired products. This application note describes the use of two different anion-exchange columns, IonPac AS11 and IonPac AS11-HC, with suppressed conductivity detection, to analyze common organic and inorganic anions in yeast and bacterial fermentation broths.

AN107: Ions (Anions) in Physiological Fluids

Instrument Type: IC

One of the most important applications of IC in clinical chemistry is the analysis of physiological fluids such as urine, plasma, and serum both for inorganic and organic anions and cations. This application note outlines the analysis of physiological fluids using ion chromatography. Part one shows the anion method, the IonPac AS11 is coupled with the Anion Self-Regenerating Suppressor (ASRS) to dramatically reduce eluent conductivity, thus allowing the use of a rapidly increasing hydroxide gradient for the separation of an extensive group of monovalent through trivalent.