Simultaneous UHPLC/MS Analyses of Explosive Compounds

Instrument Type: LCMS

We describe an ultra high performance liquid chromatography/mass spectrometry (UHPLC/MS) method to efficiently separate, detect and quantitate all four classes of explosive compounds in soil samples, including eight nitroaromatics, two nitroamines, five nitrate esters and two peroxides. The explosives were separated on a Thermo Scientific Hypersil GOLD PFP, 1.9 µm, 2.1 x 100 mm column and detected by selected ion monitoring (SIM) on an Thermo Scientific MSQ Plus Mass Detector – a fast scanning, single-quadrupole mass spectrometer.