AU168: Determination of Transition Metals in Complex Matrices

Instrument Type: IC

Chelation ion chromatography facilitates the determination of low concentrations (μg/L and lower) of transition metals in samples including seawater, brines, estuarine waters, and a variety of biological samples. Here, the authors simplify the system configuration described in Technical Note 25, using an ICS-3000 system. The separation has also been updated to include the IonPac CS5A/CG5A column set, which demonstrates improved selectivity and peak efficiency for separation of transition metals compared to the CS5.

AN108:Determination of Transition Metals in Serum and Whole Blood by Ion Chromatography

Instrument Type: IC

The determination of transition metals in physiological fluids is of considerable interest in clinical chemistry. This application note describes an attractive alternative to traditional spectroscopic methods by using the principles of ion exchange. Separation between individual metals can be enhanced or altered simply by changing eluents (pyridine-2, 6-dicarboxylic acid or oxalic acid). This figure illustrates the selectivity on an IonPac CS5A column when using a pyridine-2, 6-dicarboxylic acid eluent.