Simultaneous Analysis of Amino Acids, Acylcarnitines, and Succinylacetone in Dried Blood Spots for Research Using Nonderivatized and Derivatized Methods

Instrument Type: LCMSMS

We developed a flow injection analysis-tandem mass spectrometry (FIA-MS/MS) research methods for simultaneous detection and quantification of 12 amino acids, 18 acylcarnitines, and succinylacetone in dried blood spots and compare derivatization and nonderivatization sample preparation methods.