AN1000: Direct Determination of Small Organic Acids in Sea Water by IC-MS

Instrument Type: ICMS

This application demonstrates a 2D-IC-MS system that allows low levels of small organic acids (C1–5) to be analyzed in a high-ionic-strength matrix. The first dimension of the system separates the low-level analytes from the matrix while the second dimension resolves each of the target analytes. The mass spectrometer confirms identity and achieves low detection limits for a sensitive and selective assay. No special sample preparation was required and the results show good precision and reproducibility.