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USP-aligned ion chromatographic assay of magnesium sulfate using a next-generation electrolytic suppressor
Description
This application note demonstrates a USP-aligned ion chromatography method for quantitative assay of magnesium sulfate using the Dionex IonPac CS16 column and NGES-C electrolytic suppressor. The method uses suppressed conductivity detection with 48 mM MSA and meets USP system suitability criteria, including Mg/Ca resolution, tailing factor, and %RSD. Linearity was confirmed from 10–300 µg/mL, and sample assays fell within 98–102% with low RSDs. The NGES-C improves baseline stability, noise reduction, and robustness for routine pharmaceutical QC.| Market: | Pharma; BioPharma |
| Keywords: | Pharmacopeia, USP, IonPac CS16 column, NGES-C, Pharmaceuticals: NGES suppressor |
| Matrix: | Magnesium Sulfate |
| Author: | Chanakya Thaker; Neil Rumachik |
For Research Use Only. Not for use in diagnostic procedures.