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AN001434: Identification of Plastic Additives in Pharmaceutical Packaging using a Fully Automated Parallel Extraction Evaporator System and UHPLC-HRMS

Description
This application note demonstrates the successful use of the fully automated the EXTREVA ASE system for the extraction of plastic additives in packaging. Additives were confidently identified by liquid chromatography and Orbitrap-based high-resolution accurate mass (HRAM) mass spectral analysis. The EXTREVA ASE technique delivers comparable or more efficient extractions than the traditional 10 h static liquid extraction. The EXTREVA ASE system combines extraction and evaporation in one unit, which significantly reduces manual labor cost and increases sample throughput.Market: | Pharma |
Keywords: | Accelerated Solvent Extractor, Additives, ASE, Pressurized Fluid Extraction, E&L, inhaler, Thermo Scientific EXTREVA ASE, AN 001434 |
Matrix: | polymer |
Author: | Jingli Hu, Jeffrey Rohrer |
Affiliation: | Thermo Fisher Scientific, Sunnyvale, CA USA |
For Research Use Only. Not for use in diagnostic procedures.