Thermo Scientific AppsLab Library: Analysis of poloxam 188 and Tween 80 in adeno-associated virus vector preparation by CAD (Vanquish Core结合CAD检测器同时测定腺相关病毒载体制剂中的泊洛沙姆188和吐温80)

Rate

Ask the Expert

Suggest an Application

Find methods for your needs

Your browser or browser version is not supported. AppsLab Library and Virtual Column minimum browser requirements: Microsoft® Internet Explorer® 11, Mozilla® Firefox® 36 or Google® Chrome™ 41.

Analysis of poloxam 188 and Tween 80 in adeno-associated virus vector preparation by CAD (Vanquish Core结合CAD检测器同时测定腺相关病毒载体制剂中的泊洛沙姆188和吐温80) Be the first to rate this application

analysis poloxam 188 tween 80 adenoassociated virus vector preparation by cad vanquish core结合cad检测器同时测定腺相关病毒载体制剂中的泊洛沙姆188和吐温80

#	Compound Name	CAS Number	Compound Class	RT (min)
1	Tween 80	9005-65-6	standard	3.36
2	Polyethylene-polypropylene glycol	9003-11-6	standard	4.88

Description

In this paper, a simple and efficient HPLC method was established by using Vanquish Core high performance liquid chromatography (Vanquish Core) combined with general quality detector-Charged Aerosol Detection(CAD). It can meet the needs of simultaneous determination of Poloxam 188 and Tween 80 in adeno-associated virus (AAV) vector preparation. The method has good stability and high sensitivity. The wide linear range is suitable for the determination of different concentrations of samples, and can be used as an effective means for the control of excipient residues in drugs such as Poloxam 188

Market:	BioPharma
Keywords:	Tween 80, CAD, Vanquish Core, Poloxam 188
Matrix:	adeno-associated virus vector preparation
Author:	yu.cui; jianming.cao; yan.jin
Affiliation:	Thermo Fisher Scientific

Uploaded on 6/8/2022.

For Research Use Only. Not for use in diagnostic procedures.