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AN000900: Determination of Phosphite and Phosphate in Ibandronate Sodium
Description
The goal of this work is to design an ion chromatography method that uses a Dionex IonPac AS28-Fast-4μm anion exchange column, electrolytically generated KOH eluent, and suppressed conductivity detection to determine phosphite and phosphate in ibandronate sodium. The method proposed in this application note was validated following the guidelines outlined in USP General Chapter <1225>, Validation of Compendial Procedures to meet the requirements specified for phosphite and phosphate quantification prescribed in the proposed USP Ibandronate Sodium monograph.| Market: | Pharma |
| Keywords: | HPIC, RFIC, Dionex Integrion HPIC, Dionex IonPac AS28-Fast-4μm column, bisphosphonates, Dionex ADRS 600, AN 000900 |
| Matrix: | DI water |
| Author: | Sachin Patil and Jeffrey Rohrer |
| Affiliation: | Thermo Fisher Scientific, Sunnyvale, CA, USA |
For Research Use Only. Not for use in diagnostic procedures.
