Rate
Ask the Expert
Suggest an Application
Add to Favorites
Download eWorkflow
CreateParts List
Tell a Friend
PrintFind methods for your needs
Simultaneous reversed-phase and anion-exchange method scouting with a dual system for mRNA impurity determination
Description
The Thermo Scientific™ Vanquish™ Duo for Dual LC combined with the Method Scouting Kit offers a valuable solution for determining the most promising chromatographic conditions in a time-effective manner. With the Vanquish Duo system, two independent chromatographic chemistries (IEX and IP-RP) are scouted on the same system at the same time, which enables faster method development and requires less instrumentation. In this work, a large number of mobile phase conditions are tested with minimal preparation work.| Market: | BioPharma |
| Keywords: | Method Development, ion-exchange chromatography, chromatography, Dual-LC, ion-pairing reversed-phase, mRNA, mRNA purification, solvent scouting, Vanquish Duo UHPLC |
| Matrix: | TE buffer, transcription buffer |
| Author: | Denis Andrei Ispan, Mauro De Pra, Katherine Lovejoy |
| Affiliation: | Thermo Fisher Scientific, Germering, Germany |
For Research Use Only. Not for use in diagnostic procedures.
