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AN74121: Determination of Glycoprotein Sialic Acid Composition using HPAE-PAD in Dual Eluent Generation Cartridge Mode Be the first to rate this application


This application note demonstrates that the AU180 method for sialic acid determination of glycoproteins could be successfully modified for use with a Dionex CarboPac PA20-1 mm column and HPAE-PAD in dual eluent generation cartridge mode.
Market: BioPharma
Keywords: Electrochemical detection, Sialic acids, Dionex ICS-6000 HPIC system, Dual EGC Mode, Dionex CarboPac PA20-1 mm column, N-acetylneuraminic acid (Neu5Ac), N-glycolylneuraminic acid (Neu5Gc), AN 74121, TN 20, TN 70671, TN20, TN70671
Matrix: Acid-hydrolyzed glycoprotein
Author: Jingli Hu and Jeffrey Rohrer
Affiliation: Thermo Fisher Scientific, Sunnyvale, CA USA
Uploaded on 6/22/2021.

For Research Use Only. Not for use in diagnostic procedures.