Thermo Scientific AppsLab Library: Determination of inborn errors of metabolism: Quantification of amino acids and acylcarnitines in dried blood spots by FIA-MS/MS for clinical research

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Determination of inborn errors of metabolism: Quantification of amino acids and acylcarnitines in dried blood spots by FIA-MS/MS for clinical research Be the first to rate this application

amino acids acylcarnitines dried blood spots

Description

Implementation of a flow injection analysis-tandem mass spectrometry (FIA-MS/MS) method for simultaneous quantification of 13 amino acids and 13 acylcarnitines in dried blood spots. Newborn screening (NBS) is a public health program provided by most of the countries around the world aimed at screening newborns for a list of serious genetic and metabolic disorders.1-4 Determination of the amino acids and acylcarnitines profile is an integral part of the newborn screening programs.

Market:	Clinical Research
Keywords:	Amino acids, Clinical Research, Triple Quadrupole, acylcarnitines, mass spectrometry, disorders, dried blood spots, FIA-MS/MS, genetic, inborn errors of metabolism (IEM), metabolic, newborn screening, non-derivatized, TSQ Fortis MS
Matrix:	Blood, dried blood, dried blood spots
Author:	Mariana Barcenas, Thermo Fisher Scientific, Les Ulis, France
Affiliation:	Thermo Fisher Scientific

Uploaded on 9/30/2020.

For Research Use Only. Not for use in diagnostic procedures.