Chromatographic method for aggregate and fragment analysis of Pertuzumab i.e IgG1 Mab using SEC column.
DescriptionAnalysis of protein aggregation and fragment of pertuzumab by size-exclusion chromatography, showing the universal applicability of the Thermo Scientific MAbPac SEC-1 column for aggregate and fragment analysis. Aggregate analysis is major CQA for protein based drugs and requires tight monitoring and control.
|Keywords:||Biotherapeutics, HPLC, Size exclusion chromatography, MAbPac SEC-1, IgG1, Pertuzumab|
|Affiliation:||thermo Fisher Scientific, CoE Lab, Ahmedabad, India|
For Research Use Only. Not for use in diagnostic procedures.