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Automated biopharmaceutical protein digestion optimization for peptide mapping method development
Description
Combining the Thermo Scientific™ SMART Digest™ magnetic kits with the Thermo Scientific™ KingFisher™ Duo Prime purification system provides an automated approach to protein digest method optimization. A robust and reproducible, automated digestion time-course protocol to determine the optimal digest time for a biotherapeutic during development of a peptide mapping method.| Market: | BioPharma |
| Keywords: | Biotherapeutics, mAbs, digest optimization, IgG1, KingFisher Duo Prime purification system, Q Exactive Plus, SMART Digest magnetic kit, time-course, Vanquish UHPLC system |
| Matrix: | mAb standards |
| Author: | Tom Buchanan |
| Affiliation: | Thermo Fisher Scientific |
For Research Use Only. Not for use in diagnostic procedures.