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Straightforward transfer of an EP method for impurity analysis of chlorhexidine from an Agilent 1260 Infinity LC system to a Vanquish Core HPLC system
Description
The application demonstrates the simple transfer of a compendial LC method for the analysis of chlorhexidine impurities from an Agilent 1260 Infinity LC system to a Vanquish Core HPLC system. Equivalent chromatographic results are obtained with both instruments. Enhanced hardware features of the Vanquish Core HPLC system enable the flexible adjustments of the overall system gradient delay volume, which facilitates fine-tuning of retention time matches during the transfer.Market: | Pharma |
Keywords: | Chlorhexidine, HPLC method transfer, Agilent 1260 Infinity LC system, Vanquish Core HPLC System, European Pharmacopoeia |
Matrix: | eluent A |
Author: | Maria Grübner |
Affiliation: | Thermo Fisher Scientific, Germering, Germany |