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Description
This application note describes an IC-based method that uses a Thermo Scientific™ Dionex™ IonPac™ CS5A cation-exchange column, pyridine-2,6-dicarboxylic acid (PDCA) eluent, post-column reaction with 4-(2-pyridylazo)resorcinol (PAR), and absorbance detection to determine copper in cupric chloride. The Dionex IonPac CS5A high-resolution column is designed for fast and accurate determination of the transition and lanthanide metals in a variety of samples. The method proposed here was validated following the guidelines outlined in USP General Chapter <1225>, Validation of Compendial Procedures.| Market: | Pharma |
| Keywords: | copper, Pharmaceuticals, USP monograph, Dionex IonPac CS5A Column, drug substance |
| Matrix: | 2 mM HNO3 |
| Author: | Sachin Patil and Jeffrey Rohrer |
| Affiliation: | Thermo Fisher Scientific, Sunnyvale, California, USA |
For Research Use Only. Not for use in diagnostic procedures.
